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407317

Anti-Integrin β6 Mouse mAb (442.5C4)

liquid, clone 442.5C4, Calbiochem®

Synonym(s):

Integrin β₆ Detection Antibody, Mouse Anti-Integrin β₆, Integrin β6 Detection Antibody

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About This Item

NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
442.5C4, monoclonal
Species reactivity:
human
Application:
—
Citations:
4
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biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

442.5C4, monoclonal

form

liquid

does not contain

preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA
Flow Cytometry (1:50-1:100)
Immunoblotting (1:50-1:100)
Immunoprecipitation (1:50-1:100)
Paraffin Sections (1:50-1:100))

isotype

IgG

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ITGB6(3694)

General description

Mouse monoclonal antibody supplied as undiluted ascites. Recognizes the β6 integrin chain.
Recognizes the β6 integrin chain.
This Anti-Integrin β₆ Mouse mAb (442.5C4) is validated for use in ELISA, FC, Immunoblotting, IP, Paraffin Sections for the detection of Integrin β₆.

Immunogen

Human
recombinant, human αvβ₆

Application

ELISA (see comments)

Flow Cytometry (1:50-1:100)

Immunoblotting (1:50-1:100)

Immunoprecipitation (1:50-1:100)

Paraffin Sections (1:50-1:100)

Physical form

Undiluted ascites.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Miller, L.A., et al. 2001. J. Histochem. Cytochem.49, 41.
Breuss, J.M., et al. 1995. J. Cell Sci.108, 2241.
Hynes, R.O. 1992. Cell.69, 11.
Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.
Hynes, R.O. 1987. Cell.45, 549.
This antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Johannes Notni et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 58(4), 671-677 (2016-12-17)
Expression of the cellular transmembrane receptor αvβ6 integrin is essentially restricted to malignant epithelial cells in carcinomas of a broad variety of lineages, whereas it is virtually absent in normal adult tissues. Thus, it is a highly attractive target for
Ludmila Prudkin et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(5), 668-678 (2009-03-10)
Epithelial-to-mesenchymal transition is a process in which cells undergo a developmental switch from an epithelial to a mesenchymal phenotype. We investigated the role of this phenomenon in the pathogenesis and progression of adenocarcinoma and squamous cell carcinoma of the lung.
EANM'16.
European journal of nuclear medicine and molecular imaging, 43(Suppl 1), 1-734 (2016-09-22)
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Global Trade Item Number

SKUGTIN
407317-100UL04055977188288