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444221

MMP-1/MMP-9 Substrate

Name: MMP-1/MMP-9 Substrate
Brand: MM

≥95% (HPLC), Fluorescent MMP Substrate, solid

Synonym(s):

MMP-1/MMP-9 Substrate, Fluorogenic

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About This Item

Empirical Formula (Hill Notation):

C₄₉H₆₈N₁₄O₁₂S

Molecular Weight:

1077.22

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥95% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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Properties

Product Name

MMP-1/MMP-9 Substrate, Fluorogenic, An excellent quenched fluorescence substrate for MMP-1 and MMP-9.

Quality Level

100

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

yellow

solubility

50% acetic acid: 10 mg/mL

fluorescence

λ_ex ~365 nm, λ_em ~450 nm

shipped in

ambient

storage temp.

−20°C

Description

General description

An excellent quenched fluorescence substrate for MMP-1 and MMP-9 (excitation maximum: 365 nm; emission maximum: 450 nm). Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining K_i values. Excitation max: ~365 nm; emission max: ~450 nm.

Biochem/physiol Actions

Cell permeable: no

Primary Target
MMP-1, MMP-9

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Other Notes

Bickett, D.M., et al. 1993. Anal. Biochem. 212, 58.

{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c