444229
MMP-8, Human Neutrophil
Synonym(s):
Matrix Metalloproteinase 8, Human Neutrophil Collagenase, Collagenase-2
assay
≥90% (SDS-PAGE)
form
liquid
specific activity
≥40 mU/mg protein
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
foreign activity
other MMP, none detected
shipped in
wet ice
storage temp.
−70°C
Quality Level
Disclaimer
Toxicity: Standard Handling (A)
General description
Native pro-MMP-8 from stimulated human neutrophils. MMP-8 is an N-linked, complex glycoprotein that preferentially hydrolyzes Type I collagen versus Types II and III. Activated MMP-8 is inhibited by TIMP-1. Requires activation just prior to use. MW 58800/44000.
Other Notes
Deschamps, A. M., et al. 2005. Circulation111, 1166.
Mallya, S.K., et al. 1990. Biochemistry 29, 10628.
Marcy, A.I., et al. 1991. Biochemistry30, 6476.
Stricklin, et al. 1983. Biochemistry22, 61.
Mallya, S.K., et al. 1990. Biochemistry 29, 10628.
Marcy, A.I., et al. 1991. Biochemistry30, 6476.
Stricklin, et al. 1983. Biochemistry22, 61.
Packaging
Please refer to vial label for lot-specific concentration.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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