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454428

4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide potassium salt

Name: 4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide potassium salt
Brand: MM

≥98% (HPLC), crystalline solid, hexosaminidase A substrate, Calbiochem^®

Synonym(s):

4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt, 4-Methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside, K

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₀NO₁₁S · K

Molecular Weight:

497.51

UNSPSC Code:

51111800

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

crystalline solid

Quality level:

100

Storage condition:

OK to freeze, desiccated, protect from light

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Properties

Product Name

4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt, Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM2 gangliosidosis genotypes.

Quality Level

100

assay

≥98% (HPLC)

form

crystalline solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated, protect from light

color

white

solubility

water: 20 mg/mL

fluorescence

λ_ex 360 nm, λ_em 440 nm

shipped in

ambient

storage temp.

−20°C

Description

General description

Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM₂ gangliosidosis genotypes. Excitation maximum: ~360 nm; emission maximum: ~440 nm.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Greloner, E.E., and Wenger, D.A. 1987. Prenat. Diag. 7, 419.
Bayleran, J., et al. 1984. Clin. Chim. Acta143, 73.
Inui, K., and Wenger, D.A. 1984. Clin. Genet.25, 93.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c