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Merck
CN

454454

Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide

≥98% (HPLC), solid, human leukocyte elastase substrate, Calbiochem®

Synonym(s):

Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide

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About This Item

Empirical Formula (Hill Notation):
C27H38N6O9
CAS Number:
70967-90-7
Molecular Weight:
590.63
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00077137

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Product Name

Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide, Soluble, specific substrate for human leukocyte elastase.

SMILES string

[N+](=O)([O-])c1ccc(cc1)N[C@@H](C(C)C)C(=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCC(=O)OC)C)C

InChI

1S/C27H38N6O9/c1-15(2)23(30-18-8-10-19(11-9-18)33(40)41)26(38)31-25(37)20-7-6-14-32(20)27(39)17(4)29-24(36)16(3)28-21(34)12-13-22(35)42-5/h8-11,15-17,20,23,30H,6-7,12-14H2,1-5H3,(H,28,34)(H,29,36)(H,31,37,38)/t16-,17-,20-,23-/m0/s1

InChI key

JWYKDZIEIWGSBN-OSAZLGQLSA-N

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

off-white

solubility

ethanol: 1 mg/mL
DMF: 5 mg/mL
DMSO: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Related Categories

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Biochem/physiol Actions

Cell permeable: no
Primary Target
Substrate for human leukocyte elastase
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Standard Handling (A)

General description

Soluble specific substrate for human leukocyte elastase. Is 200-fold more sensitive than the conventional substrate.
Soluble, specific substrate for human leukocyte elastase. Is 200-fold more sensitive than the conventional substrate. Cleavage of substrate can be monitored at ~405 nm.

Other Notes

MeOSuc-Ala-Ala-Pro-Val-pNA, MeOH

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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