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Merck
CN

48-622MAG

MILLIPLEX® Phospho/Total JNK Signaling Panel

Premixed JNK Phospho/Total 2-Plex Cell Signaling Panel

Synonym(s):

JNK ELISA, JNK assay, JNK multiplex panel, JNK phosphorylation, JNK signaling, SAPK assay, c-Jun N-terminal kinase, stress-activated kinase, total JNK

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161503
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Quality Level

species reactivity

human, rat, mouse

technique(s)

multiplexing: suitable

input

cell lysate

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

JNK, or c-Jun N-terminal kinase, is a key component of the MAPK pathway involved in cellular responses to stress, inflammation, and apoptosis. Phosphorylation at Thr183/Tyr185 activates JNK, influencing gene expression and cell fate decisions.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 2 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: JNK (Phospho-Thr183/Tyr185), JNK (Total)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate Control Assays).

Biochem/physiol Actions

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Features and Benefits

  • Dual measurement of phospho and total JNK for accurate normalization
  • Supports investigation of stress-activated MAPK signaling
  • Multiplex format conserves sample and reagents
  • Compatible with a wide range of cell and tissue lysates
  • Verified for reproducibility and robust performance

Legal Information

Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Information

新产品
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Related Content

Uncover how cells communicate with MILLIPLEX® cell signaling multiplex assays. Multiplexing with cell signaling phosphoprotein assays based on Luminex® xMAP® technology helps researchers measure phosphoproteins and total proteins within the same or different pathways from a single sample.

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