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Merck
CN

492018

NP-40 Alternative, PROTEIN GRADE® Detergent, 10% Solution, Sterile-Filtered

A non-ionic surfactant useful for the isolation and purification of functional membrane protein complexes. This detergent has been purified to reduce levels of contaminating aldehydes, metals, peroxides, and salts.

Synonym(s):

Nonylphenyl Polyethylene Glycol

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About This Item

CAS Number:
9016-45-9
UNSPSC Code:
12161902
NACRES:
NA.25
MDL number:
MFCD00132851

Key Documents

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Product Name

NP-40 Alternative, PROTEIN GRADE® Detergent, 10% Solution, Sterile-Filtered, A non-ionic surfactant useful for the isolation and purification of functional membrane protein complexes. This detergent has been purified to reduce levels of contaminating aldehydes, metals, peroxides, and salts.

SMILES string

O(CCOc1ccc(cc1)CCCCCCCCC)CCO

InChI

1S/C19H32O3/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)22-17-16-21-15-14-20/h10-13,20H,2-9,14-17H2,1H3

InChI key

BLXVTZPGEOGTGG-UHFFFAOYSA-N

description

RTECS - MD0905000

product line

Calbiochem®

form

solution

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

≤200 μM Aldehyde
≤200 μM peroxide

color

clear colorless

conductivity

≤50 μmho

CMC

50 - 300 μM

solubility

water: soluble

application(s)

(Isolating membrane proteins)

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Related Categories

Disclaimer

Toxicity: Irritant (B)

General description

A non-ionic surfactant used in the isolation and purification of functional membrane protein complexes and in two-dimensional gel electrophoresis (2DGE). Similar in usage to NP-40 and TRITON™ X-100 (Cat. No. 648462). Purified to reduce levels of contaminating aldehydes, metals, peroxides, and salts. CMC: 50-300 µM.
A non-ionic surfactant useful for the isolation and purification of functional membrane protein complexes. This detergent has been purified to reduce levels of contaminating aldehydes, metals, peroxides, and salts.

Other Notes

Ripoche, P., et al. 1982. Biochim. Biophys. Acta693, 497.

Physical form

10% aqueous solution.

Preparation Note

Following initial use, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
PROTEIN GRADE is a registered trademark of Merck KGaA, Darmstadt, Germany
Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Information

监管及禁止进口产品
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Tsung-Han S Hsieh et al.
Molecular cell, 78(3), 539-553 (2020-03-28)
Whereas folding of genomes at the large scale of epigenomic compartments and topologically associating domains (TADs) is now relatively well understood, how chromatin is folded at finer scales remains largely unexplored in mammals. Here, we overcome some limitations of conventional

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