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494459

n-Octyl-β-D-glucopyranoside

Name: <i>n</i>-Octyl-β-D-glucopyranoside
Brand: MM

CAS 29836-26-8 is a non-ionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles.

Synonym(s):

n-Octyl-β-D-glucopyranoside, OG, n-Octylglucoside

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₂₈O₆

CAS Number:

29836-26-8

Molecular Weight:

292.37

UNSPSC Code:

12161902

NACRES:

NA.21

MDL number:

MFCD00063288

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Properties

Quality Level

300

assay

≥98% (HPLC)

form

solid

mol wt

292.38 g/mol

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

aggregation number

impurities

≤0.05% n-octanol, ≤35 mg/dL glucose

color

white

CMC

20 - 25 mM

mp

106.8 °C (at 984 hPa)

solubility

water: 100 mg/mL

shipped in

ambient

storage temp.

15-25°C

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)OCCCCCCCC

InChI

1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1

InChI key

HEGSGKPQLMEBJL-RKQHYHRCSA-N

Description

General description

Absorbance (10%, H₂O, 260 nm):≤0.3.

Non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. Its well–defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.

Nonionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles. Its well-defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.

Application

Tube-gel digestion: a novel proteomic approach for high throughput analysis of membrane proteins.: This article introduces a new method for analyzing membrane proteins using tube-gel digestion, which employs n-Octyl-β-D-glucopyranoside for effective solubilization of membrane proteins. This approach enhances the throughput and efficiency of proteomic analyses (Lu et al., 2005).

Mixed micellization of a nonionic-cationic surfactant system constituted by n-octyl-beta-D-glucopyranoside/dodecyltrimethylammonium bromide/H2O.: The study explores the micellization behavior of a nonionic-cationic surfactant system involving n-Octyl-β-D-glucopyranoside and its interactions. The findings are significant for understanding surfactant properties and applications in biochemical processes (del Burgo et al., 2004).

Preparation Note

Following reconstitution, store in the refrigerator (4°C), under sterile conditions. Aqueous stock solutions are stable for up to 3 months at 4°C. Solutions are susceptible to hydrolysis (especially acidic solutions) and enzymatic hydrolysis.

Other Notes

Hoshino, T., et al. 1992. J. Biol. Chem.267, 21313.
Levy, D., et al. 1992. Biochim. Biophys. Acta1107, 283.
Nunn, R.S., et al. 1992. J. Mol. Biol.228, 1259.
Lorber, B., et al. 1990. Biochim. Biophys. Acta1023, 254.
Jopski, B., et al. 1989. Biochim. Biophys. Acta978, 79.
Camm, E.L., et al. 1981. Plant Physiol.67, 1061.
Gould, R.J., et al. 1981. Biochemistry20, 6776.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c