5.04820
Cinnabarinic acid
Synonym(s):
Cinnabarinic acid, 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid
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About This Item
Empirical Formula (Hill Notation):
C14H8N2O6
CAS Number:
Molecular Weight:
300.22
UNSPSC Code:
12352106
NACRES:
NA.77
MDL number:
Form:
solid
Assay:
≥98% (HPLC)
Solubility:
DMSO: 25 mM
Color:
red
assay
≥98% (HPLC)
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
red
solubility
DMSO: 25 mM
storage temp.
−20°C
SMILES string
Nc1[c](cc2[o]c3c(nc2c1C(=O)O)c(ccc3)C(=O)O)=O
InChI
1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)
InChI key
FSBKJYLVDRVPTK-UHFFFAOYSA-N
General description
A partial, low-potency agonist highly selective for mGlu4 receptors (EC50 >100 µM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu4 receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication.
Biochem/physiol Actions
Primary Target
mGlu₄ receptors
mGlu₄ receptors
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Slight warming is required for complete solubilization.
Other Notes
Fazio, Francesco, et al. 2012. Mol. Pharmacol.81, 643.
Volpi, C., et al. 2012. Neuropharmacol.63, 501.
Hiramatsu, R., et al. 2008. J. Cell Biochem.103, 42.
Volpi, C., et al. 2012. Neuropharmacol.63, 501.
Hiramatsu, R., et al. 2008. J. Cell Biochem.103, 42.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Certificates of Analysis (COA)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 5048200001 | 04055977243550 |