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Merck
CN

5.04866

UCOE® Expression Vector - Mouse 3.2 kb Hygro Set - Novagen®

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About This Item

UNSPSC Code:
41105500
NACRES:
NA.51

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manufacturer/tradename

Novagen®

Quality Level

100

storage condition

OK to freeze

storage temp.

−20°C

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General description

UCOE® (Ubiquitous Chromatin Opening Element) expression technology demonstrates major improvements in gene expression in stably-transfected mammalian cells. Over 50% of UCOE derived clones have higher expression than the best non-UCOE derived vectors. UCOE vectors may be used to express antibodies, receptors, enzymes, cytokines, and other similar sized biological material. UCOE technology is convenient and easy to use, because it integrates with industry standard platforms (e.g. CHO cells, CMV promoters, plasmids, transfection agents, media, etc...).

The set includes following components:
• 1 x 10 µg DNA
• 1 x 10 µg DNA (Negative control)
Antibiotic resistance: Hygromycin




THIS PRODUCT IS ONLY AVAILABLE FOR SALE TO ACADEMIC INSTITUTIONS OR NOT-FOR-PROFIT ENTITIES FOR RESEARCH USE. FOR INFORMATION ON COMMERCIAL LICENSING OF THE UCOE TECHNOLOGY, INCLUDING TO COMMERCIAL ENTITIES, PLEASE CONTACT Marie Azzaria (Marie.Azzaria@emdmillipore.com) or Jamie Hoberg (James.Hoberg@emdmillipore.com).

Application

UCOE (Ubiquitous Chromatin Opening Elements) technology is a breakthrough solution for sustained recombinant protein production and cell line development in mammalian protein expression systems.

Legal Information

NOVAGEN is a registered trademark of Merck KGaA, Darmstadt, Germany
UCOE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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Related Content

Introducing UCOE®mammalian gene expression technology

"Before going through time-consuming optimization protocols, try EMD Millipore’s NEW ubiquitous chromatin opening element (UCOE®) technology. UCOE® expression technology gives a 9- to 56-fold boost in the production level of a secreted protein (Erythropoietin). A single UCOE® element placed upstream of the 5’ end of the promoter and transgene is sufficient to boost expression twenty-fold or more. CHO-K1 cells transfected with erythropoietin expression constructs with or without UCOE® expression technology. With UCOE® technology, you can: • Achieve grams of protein in less than 30 days • Boost expression levels up to 20-fold higher than possible with conventional vectors • Enhance industry-standard platforms, such as CHO cells and CMV promoters"

Data Sheet-504866-1SET

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