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5.05818

Scopolamine Hydrobromide

≥99% (HPLC), mAChR antagonist, solid

Synonym(s):

Scopolamine Hydrobromide, Muscarinic Acetylcholine Receptor (mAChR) Antagonist, Scopolamine, Levo-duboisine, Hyoscine, Scopoderm

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About This Item

Empirical Formula (Hill Notation):
C17H21NO4 · xHBr
CAS Number:
114-49-8
Molecular Weight:
303.35 (free base basis)
MDL number:
MFCD00012647
UNSPSC Code:
12352116
NACRES:
NA.77
Assay:
≥99% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, protect from light
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Product Name

Scopolamine Hydrobromide,

assay

≥99% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

off-white

solubility

H2O: 100 mM

storage temp.

2-8°C

SMILES string

[Br].N1([C@@H]2[C@@H]3O[C@@H]3[C@@H]1CC(C2)OC(=O)[C@H](CO)c4ccccc4)C

InChI

1S/C17H21NO4.Br/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;/t11?,12-,13+,14+,15-,16+;/m1./s1

InChI key

XUZPYCBMTSSDHK-AKTDCHNFSA-N

General description

A competitive, non-selective antagonist for muscarinic acetylcholine receptors (mAChR). Most effective at treating motion sickness. It is also a research tool for inducing memory impairment in vivo. Frequently used in researches related to learning, memory and Alzheimer′s dementia.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Klinkenberg, I., et al. 2010. Neurosci Biobehav Rev34, 1307.
Aparkes. W. 1995. Psychopharmacologia.7, 1.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

Regulatory Information

涉药品监管产品

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Global Trade Item Number

SKUGTIN
505818000104055977263039