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538909

Prostaglandin D₂

Name: Prostaglandin D<SUB>2</SUB>
Brand: MM

≥98% (HPLC), adenylate cyclase activator, solid

Synonym(s):

Prostaglandin D₂, PGD₂

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₃₂O₅

CAS Number:

41598-07-6

Molecular Weight:

352.47

UNSPSC Code:

12352211

NACRES:

NA.77

MDL number:

MFCD00077857

eCl@ss:

42020658

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze

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Properties

Product Name

Prostaglandin D₂, Major prostaglandin metabolite in brain and an important inflammatory mediator in mast cells.

Quality Level

100

description

Merck USA index - 14, 7879

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white

solubility

ethanol: 100 mg/mL, acetone: soluble, ethyl acetate: soluble, methanol: soluble

shipped in

wet ice

storage temp.

−20°C

SMILES string

O[C@@H]1[C@@H]([C@H](C(=O)C1)\C=C\[C@@H](O)CCCCC)C\C=C/CCCC(=O)O

InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1

InChI key

BHMBVRSPMRCCGG-OUTUXVNYSA-N

Description

General description

Major prostaglandin metabolite in the brain and an important inflammatory mediator in mast cells. Neuromodulator that evokes nerve-mediated Cl^- secretion. Stimulates adenylate cyclase.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Adenylate cyclase

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C).

Other Notes

Horn, E.H., et al. 1995. Clin. Sci. 89, 91.
Frieling, T., et al. 1994. Am. J. Physiol. 266, G132.
Huttemeier, P.C., et al. 1993. Prostaglandins 45, 177.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302,H360

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c