539142
Proteasome Substrate III, Fluorogenic
≥98% (HPLC), amorphous solid, proteasome substrate, Calbiochem®
Synonym(s):
Proteasome Substrate III, Fluorogenic, Suc-LLVY-AMC, Chymotrypsin Substrate III, Fluorogenic
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About This Item
Empirical Formula (Hill Notation):
C40H53N5O10
Molecular Weight:
763.88
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
amorphous solid
Storage condition:
OK to freeze, protect from light
Product Name
Proteasome Substrate III, Fluorogenic, Proteasome Substrate III, Fluorogenic, is a substrate for proteasome. Also acts as a substrate for calpain, chymotrypsin, and ingensin.
Quality Segment
assay
≥98% (HPLC)
form
amorphous solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 50 mg/mL
fluorescence
λex ~380 nm, λem ~460 nm
shipped in
ambient
storage temp.
−20°C
General description
Fluorogenic proteasome substrate. Also acts as a substrate for calpain, chymotrypsin, and ingensin.
Biochem/physiol Actions
Cell permeable: no
Inhibits serine proteases and cysteine proteases.
Primary Target
Proteasome
Proteasome
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Anderson, M., et al. 1999. Exp. Eye Res.69, 129.
Rock, K.L., et al. 1994. Cell 78, 761.
Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun.196, 1195.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.
Rock, K.L., et al. 1994. Cell 78, 761.
Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun.196, 1195.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.
Suc-Leu-Leu-Val-Tyr-AMC
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 539142-5MG | 04055977195552 |