567028
3-Morpholinosydnonimine hydrochloride
≥98% (HPLC), solid, nitric oxide (NO) donor, Calbiochem®
Synonym(s):
SIN-1, Hydrochloride, 3-Morpholinosydnonimine, HCl
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About This Item
Empirical Formula (Hill Notation):
C6H10N4O2 · xHCl
CAS Number:
Molecular Weight:
170.17 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Product Name
SIN-1, Hydrochloride, Nitric oxide (NO) donor.
Quality Level
description
RTECS - WU7687800
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 10 mg/mL, ethanol: 10 mg/mL, water: 25 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
[Cl-].[n]2(n[o+]c(c2)N)N1CCOCC1
InChI
1S/C6H11N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5H,1-4,7H2;1H/q+1;/p-1
InChI key
ZRFWHHCXSSACAW-UHFFFAOYSA-M
General description
Nitric oxide (NO) donor. Spontaneously decomposes to yield NO and superoxide anion radicals. Also inhibits the release of plasminogen activator inhibitor (PAI) from stimulated platelets. Unstable in aqueous solution.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Nitric oxide (NO) donor
Nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no
Preparation Note
Unstable in aqueous solution; reconstitute just prior to use. Following reconstitution, aliquot and freeze (-20°C).
From Catalog:
Desc. Field- added "Unstable in aqueous solution."
From Catalog:
Desc. Field- added "Unstable in aqueous solution."
Other Notes
Gow, A.J., et al. 2000. Am. J. Physiol. 278, C1099.
Gergel, D., et al. 1995. J. Biol. Chem.270, 20922.
de Groot, H., et al. 1993. FEBS Lett.315, 139.
Lipton, S.A., et al. 1993. Nature364, 626.
Drummer, C., et al. 1991. Thromb. Res.63, 553.
Omar, B.A., et al. 1990. Free Radical Biol. Med.9, 465
Gergel, D., et al. 1995. J. Biol. Chem.270, 20922.
de Groot, H., et al. 1993. FEBS Lett.315, 139.
Lipton, S.A., et al. 1993. Nature364, 626.
Drummer, C., et al. 1991. Thromb. Res.63, 553.
Omar, B.A., et al. 1990. Free Radical Biol. Med.9, 465
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 567028-20MG | 04055977267136 |