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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.54
biological source
Staphylococcus aureus
Quality Level
form
liquid
specific activity
≥100 units/mg protein
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
ambient
storage temp.
2-8°C
General description
Native sphingomyelinase from Staphylococcus species. May be applied exogenously to initiate the sphingomyelin signaling pathway. Has very little activity on phosphatidylcholine.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 250 mM phosphate buffer, 50% glycerol, pH 7.5.
Preparation Note
Following initial use, aliquot and refrigerate (4°C).
Other Notes
Galve-Roperh, I., et al. 1997. Brain Res. Mol. Brain Res.52, 90.
Jarvis, W.D., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 73.
Mathias, S., et al. 1993. Science259, 519.
Raines, M.A., et al. 1993. J. Biol. Chem.268, 14572.
Jarvis, W.D., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 73.
Mathias, S., et al. 1993. Science259, 519.
Raines, M.A., et al. 1993. J. Biol. Chem.268, 14572.
One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of trinitrophenylaminolauryl (TNPAL)-sphingomyelin per min at 37°C, pH 7.4.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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