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Merck
CN

573114

SMCC

Synonym(s):

SMCC, Succinimidyl- trans-4-(N-maleimidylmethyl)cyclohexane-1-carboxylate, Succinimidyl-trans-4-(N-maleimidylmethyl)cyclohexane-1-carboxylate

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About This Item

Empirical Formula (Hill Notation):
C16H18N2O6
CAS Number:
Molecular Weight:
334.32
UNSPSC Code:
41116133
NACRES:
NA.23
MDL number:
Assay:
≥97% (HPLC)
Form:
solid
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assay

≥97% (HPLC)

Quality Segment

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated

color

white

solubility

DMF: 10 mg/mL, acetonitrile: soluble

shipped in

ambient

storage temp.

−20°C

SMILES string

N3(C(=O)CCC3=O)OC(=O)C1CCC(CC1)CN2C(=O)C=CC2=O

InChI

1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2

InChI key

JJAHTWIKCUJRDK-UHFFFAOYSA-N

General description

Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Cross-links both a sulfhydryl group and a free amine group. Useful for sequential conjugation to minimize polymerization.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Caruelle, D., et al. 1988. Anal. Biochem.173, 328.
Nashat, A.H., et al. 1998. Biotechnol. Bioeng.60, 137.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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