575003-M
α-Synuclein A53T, Human, Recombinant, E. coli
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About This Item
NACRES:
NA.77
UNSPSC Code:
12352202
Form:
liquid
Assay:
≥95% (SDS-PAGE)
assay
≥95% (SDS-PAGE)
Quality Segment
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
storage temp.
−20°C
General description
Recombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. α-synuclein is an acidic neuronal protein of 140 amino acids that has been implicated in the pathogenesis of Parkinson′s disease and related neurodegenerative disorders. α-Synuclein (A53T) is a point mutant of the α-synuclein gene that has been linked to autosomal dominant early onset Parkinson′s Disease (PD). The apparent molecular weight on SDS-PAGE is ~19-20 kDa.
Physical form
In 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Lashuel, H.A., et al. 2002. J. Mol. Biol.322, 1089.
Park, S.M., et al. 2002. Blood100, 2506.
Polymeropoulos, M.H., et al. 1997. Science276, 2045.
Park, S.M., et al. 2002. Blood100, 2506.
Polymeropoulos, M.H., et al. 1997. Science276, 2045.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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