616400-M
Tranilast
An anthranilic acid analog that acts as a potent inhibitor of VEGF- and vascular permeability factor-induced angiogenesis and collagen synthesis.
Synonym(s):
Tranilast, N-(3ʹ,4ʹ-Dimethoxycinnamoyl)anthranilic Acid
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About This Item
SMILES string
N(c2c(cccc2)C(=O)O)C(=O)\C=C\c1cc(c(cc1)OC)OC
InChI
1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
InChI key
NZHGWWWHIYHZNX-CSKARUKUSA-N
description
Merck USA index - 14, 9570
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
pale yellow
solubility
DMSO: 200 mg/mL
storage temp.
−20°C
Quality Level
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Related Categories
General description
Biochem/physiol Actions
VEGF- and vascular permeability factor-induced angiogenesis and collagen synthesis
Preparation Note
Other Notes
Isaji, M., et al. 1998. Life Sci. 63, PL71.
Isaji, M., et al. 1997. Br. J. Pharmacol. 122, 1061.
Legal Information
Disclaimer
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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