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Merck
CN

6.18607

Methanol

suitable for chromatography, LiChrosolv®

Synonym(s):

Methanol, Methyl alcohol

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About This Item

Linear Formula:
CH3OH
CAS Number:
Molecular Weight:
32.04
UNSPSC Code:
12191601
Beilstein/REAXYS Number:
1098229
MDL number:
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Product Name

Methanol, suitable for chromatography, LiChrosolv®

InChI key

OKKJLVBELUTLKV-UHFFFAOYSA-N

SMILES string

CO

InChI

1S/CH4O/c1-2/h2H,1H3

vapor density

1.11 (vs air)

vapor pressure

410 mmHg ( 50 °C)
97.68 mmHg ( 20 °C)

product line

LiChrosolv®

autoignition temp.

725 °F

expl. lim.

36 %

refractive index

n20/D 1.329 (lit.)

bp

64.7 °C (lit.)

mp

−98 °C (lit.)

density

0.791 g/mL at 25 °C (lit.)

suitability

suitable for chromatography

Quality Level

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Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany
Supelco is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

  • Mobile Phase in HPLC: Widely utilized as a polar solvent in both reversed-phase and normal-phase HPLC, suitable for various types of analytes.
  • Gradient Elution: Ideal for gradient elution techniques, enhancing the resolution and separation efficiency of complex mixtures. Pharmaceutical Quality Control: Used in the quality control of pharmaceutical products to analyze formulations, stability, and degradation products.
  • Food and Beverage Analysis: Employed in HPLC for the analysis of additives, preservatives, and flavor compounds in food and beverage samples.
  • Environmental Testing: Effective in the analysis of pollutants and contaminants in environmental samples, supporting compliance with regulatory standards and ensuring public safety.

Features and Benefits

  • High Purity: Formulated with minimal impurities, ensuring reliable and reproducible results essential for sensitive analytical applications.
  • Excellent UV Transparency: Provides optimal UV transmittance, facilitating accurate detection and enhancing sensitivity in HPLC analyses.
  • Low Evaporation Residue: Minimizes contamination risk, leading to cleaner separations and improved analytical reliability.
  • Batch-to-Batch Consistency: Ensures uniform quality and performance across different production batches, enhancing reproducibility and confidence in analytical results.

General description

Methanol is a versatile polar solvent widely used in bothreversed-phase and normal-phase HPLC. Its characteristics include highpolarity, low toxicity, and good miscibility with water, making it suitable fora variety of analytes. Methanol is particularly effective in gradient elutiontechniques, improving resolution and separation efficiency in complex mixtures,and is frequently employed in pharmaceutical quality control and food analysis.


Supelco® is a leading provider of high-quality HPLCsolvents, targeting laboratories in the pharmaceutical, environmental, and foodsafety sectors. The brand is recognized for its commitment to precision,reliability, and innovation in analytical chemistry. Supelco®′s extensive rangeof solvents ensures optimal performance and reproducibility, making it apreferred choice for professionals seeking consistent and accurate analyticalresults.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

新产品
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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Malakova J, et al.
Chromatographia, 66, 363-367 (2007)

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