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Sigma-Aldrich

Wogonin, S. baicalensis

A cell-permeable and orally available flavonoid that displays anti-inflammatory properties.

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Synonym(s):
Wogonin, S. baicalensis, 5,7-Dihydroxy-8-methoxyflavone, WOG
Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
632-85-9
Molecular Weight:
284.26
MDL number:
MFCD00017736

Quality Level

100

Assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

yellow

solubility

DMSO: 10 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C16H12O5/c1-20-15-12(19)7-10(17)14-11(18)8-13(21-16(14)15)9-5-3-2-4-6-9/h2-8,17,19H,1H3

InChI key

XLTFNNCXVBYBSX-UHFFFAOYSA-N

General description

A cell-permeable and orally available flavonoid that displays anti-inflammatory properties. Reported to suppress the release of NO by iNOS, PGE2 by COX-2, proinflammatory cytokines, and MCP-1 gene expression and NF-κB activation.

Packaging

Packaged under inert gas

Warning

Toxicity: Irritant (B)

Other Notes

Lee, S.O., et al. 2006. Biochem. Biophys. Res. Comm.351, 118.
Kim, H.P., et al. 2004. J. Pharmacol. Sci.96, 229.
Chang, Y.L., et al. 2001. Mol. Pharmacol.60, 507.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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