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Merck
CN

8.18215

Tetra-n-butylammonium hydroxide

(12.5% solution in methanol) for synthesis

Synonym(s):

Tetrabutylammonium hydroxide

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About This Item

NACRES:
NA.22
UNSPSC Code:
12352107
Assay:
13.3%
Form:
liquid
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Quality Level

assay

13.3%

form

liquid

expl. lim.

5.5-36.5 % (v/v) Methanol()

reaction suitability

core: ammonium

bp

65 °C/1013 hPa

transition temp

flash point 11 °C

density

0.81 g/cm3 at 20 °C

storage temp.

2-30°C

Application

  • Biological Acid Anion Research: Tetra-n-butylammonium hydroxide is used in the hydration structures of lactic acid, facilitating the formation of ionic clathrate hydrate with biological organic acid anions. This application is significant in the study of biological molecules and their interactions with water molecules in various conditions (Muromachi et al., 2014).
  • Pharmaceutical Analysis: It is used in the determination of calcium dobesilate in human plasma, utilizing ion-pairing extraction and high-performance liquid chromatography. This method is crucial for monitoring drug levels in patients, ensuring therapeutic efficacy and safety (Róna et al., 2001).

Analysis Note

Assay (acidimetric): 11.5 - 13.5 %
Density (d 20 °C/ 4 °C): 0.815 - 0.830


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signalword

Danger

Storage Class

3 - Flammable liquids

flash_point_f

51.8 °F

flash_point_c

11 °C

target_organs

Eyes,Central nervous system

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 1

wgk

WGK 2

Regulatory Information

危险化学品

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Global Trade Item Number

SKUGTIN
818215100004022536975290
818215025004022536430485