8.20128
Saccharin
for synthesis
Synonym(s):
Saccharin
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About This Item
Empirical Formula (Hill Notation):
C7H5NO3S
CAS Number:
Molecular Weight:
183.18
UNSPSC Code:
12352115
EC Index Number:
201-321-0
NACRES:
NA.22
MDL number:
Assay:
≥98.0% (acidimetric)
Form:
crystals
Quality Segment
assay
≥98.0% (acidimetric)
form
crystals
mp
228-230 °C
storage temp.
2-30°C
SMILES string
[S]1(=O)(=O)NC(=O)c2c1cccc2
InChI
1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
InChI key
CVHZOJJKTDOEJC-UHFFFAOYSA-N
Application
- Gabapentin-saccharin co-crystals with enhanced physicochemical properties and in vivo absorption formulated as oro-dispersible tablets.: This study presents the formulation of gabapentin-saccharin co-crystals, demonstrating improved solubility and absorption, beneficial for pharmaceutical applications (Soliman et al., 2020, doi: 10.1080/10837450.2019.1687521).
- Improving the solubility, dissolution, and bioavailability of Ibrutinib by preparing it in a coamorphous state with saccharin.: The research focuses on enhancing the bioavailability of Ibrutinib through coamorphous preparation with saccharin, which is significant for cancer treatment (Shi et al., 2019, doi: 10.1016/j.xphs.2019.04.031).
Analysis Note
Assay (acidimetric): ≥ 98.0 %
Melting range (lower value): ≥ 226 °C
Melting range (upper value): ≤ 230 °C
Identity (IR): passes test
Melting range (lower value): ≥ 226 °C
Melting range (upper value): ≤ 230 °C
Identity (IR): passes test
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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