8.20610
Glyoxal
(40% solution in water) for synthesis
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About This Item
NACRES:
NA.22
UNSPSC Code:
12352114
vapor pressure
20.2 hPa ( 20 °C)
Quality Segment
autoignition temp.
285 °C
potency
2000-5000 mg/kg LD50, oral (Rat), >2000 mg/kg LD50, skin (Rat)
pH
2-3 (20 °C in H2O)
bp
104 °C/1013 hPa
mp
-14 °C
density
1.27 g/cm3 at 20 °C
storage temp.
2-30°C
Application
- HFIP-Mediated Multicomponent Reactions: Research demonstrates the use of HFIP (Hexafluoroisopropanol) in synthesizing pyrazole-linked thiazole derivatives, highlighting a new application in organic synthesis. Glyoxal is instrumental in the development of these multifunctional structures, contributing to advanced material design (Banerjee et al., 2024).
- Peptide Stapling in Protein Engineering: A study describes peptide stapling techniques using alpha-ketoaldehydes, which crosslink amines through glyoxal-modified linkers. This approach is pivotal in creating stable peptide structures for therapeutic applications (Guo et al., 2024).
Analysis Note
Assay (acidimetric): 39.0 - 41.0 %
Density (d 20 °C/ 4 °C): 1.266 - 1.271
Density (d 20 °C/ 4 °C): 1.266 - 1.271
target_organs
Respiratory system
wgk
WGK 1
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Storage Class
10 - Combustible liquids
Certificates of Analysis (COA)
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