8.52036
Fmoc-Hyp(tBu)-OH
≥98.0% (HPLC), for peptide synthesis, Novabiochem®
Synonym(s):
Fmoc-Hyp(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-trans-4-hydroxyproline
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About This Item
Product Name
Fmoc-Hyp(tBu)-OH, Novabiochem®
Quality Level
product line
Novabiochem®
assay
≥95.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
mp
63 °C
application(s)
peptide synthesis
functional group
hydroxyl
storage temp.
15-25°C
SMILES string
N4([C@@H](C[C@H](C4)OC(C)(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C24H27NO5/c1-24(2,3)30-15-12-21(22(26)27)25(13-15)23(28)29-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,27)/t15-,21+/m1/s1
InChI key
WPBXBYOKQUEIDW-VFNWGFHPSA-N
General description
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Application
- Rational design of plant hairpin-like peptide EcAMP1: Structural–functional correlations to reveal antibacterial and antifungal activity: Discusses the use of Fmoc-Hyp(tBu)-OH in designing peptides that exhibit significant antibacterial and antifungal properties (Barashkova et al., 2022).
Analysis Note
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.50 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Legal Information
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Articles
Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 8520360001 | 04027269086503 |
| 8520360005 | 04027269086510 |
| 8520361000 | 04027269221652 |
| 8520360025 | 04027269086527 |