Skip to Content
Merck
CN

8.52052

Fmoc-His(Boc)-OH-CHA

Novabiochem®

Synonym(s):

Fmoc-His(Boc)-OH-CHA, N-α-Fmoc-N-im-t.-Boc-L-histidine cyclohexylammonium salt

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C26H27N3O6 · xC6H13N
CAS Number:
Molecular Weight:
477.51
UNSPSC Code:
12352209
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


product line

Novabiochem®

assay

≥97% (TLC), ≥97.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Boc, Fmoc

storage temp.

−20°C (−15°C to −25°C)

InChI

1S/C26H27N3O6.C6H13N/c1-26(2,3)35-25(33)29-13-16(27-15-29)12-22(23(30)31)28-24(32)34-14-21-19-10-6-4-8-17(19)18-9-5-7-11-20(18)21;7-6-4-2-1-3-5-6/h4-11,13,15,21-22H,12,14H2,1-3H3,(H,28,32)(H,30,31);6H,1-5,7H2/t22-;/m0./s1

InChI key

UDEXYAHZNOKVIG-FTBISJDPSA-N

General description

The N-im-Boc group is unstable to prolonged treatment with piperidine [1]; the utility of this derivative is therefore limited to the preparation of short sequences by Fmoc SPPS. This derivative is supplied as a CHA-salt.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

[1] P. Sieber, et al. (1987) Tetrahedron Lett., 28, 6031.

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 97 %
Purity (TLC(157B)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1110

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_c

Not applicable

Regulatory Information

新产品

This item has



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Global Trade Item Number

SKUGTIN
852052000504027269087357
852052002504027269087364