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Merck
CN

AB10557

Anti-Lhx2 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Homeobox protein LH-2, LIM HOX gene 2, LIM homeobox 2, LIM homeobox protein 2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC
Citations:
1

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

horse, bovine (93%), dog

technique(s)

immunohistochemistry: suitable

NCBI accession no.

NP_004780.1

UniProt accession no.

P50458

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... LHX2(9355)

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General description

Approx. 44 kDa
LIM homeobox 2, also known as LHX2, is a gene that belongs to the LIM homeobox family. These genes seem to play an important role in asymmetric cell division, tissue specification and differentiation of specific cell types. LHX2 is expressed in developing B-cells, the forebrain, liver, during embryonic development when limbs and organs are developing, in the optic stalk, and olfactory epithelia. Studies have shown that under-expression of LHX2 during embryonic development causes hepatic fibrosis.

Immunogen

This antibody is generated from rabbits immunized with a KLH conjugated linear peptide selected from residues of human LHX2.

Application

This Anti-Lhx2 Antibody is validated for use in IH for the detection of Lhx2.

Biochem/physiol Actions

Mouse (80%) homology.
This antibody recognizes LHX2.

Analysis Note

Control
Human hippocampal and mouse cerebellum tissue.
Evaluated by Immunohistochemistry in human hippocampal and mouse cerebellum tissue.
Immunohistochemistry Analysis: 1:100-500 dilution of this lot detected LHX2 in human hippocampal tissue and mouse cerebellum.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jin-Chong Xu et al.
Science translational medicine, 8(333), 333ra48-333ra48 (2016-04-08)
Translating neuroprotective treatments from discovery in cell and animal models to the clinic has proven challenging. To reduce the gap between basic studies of neurotoxicity and neuroprotection and clinically relevant therapies, we developed a human cortical neuron culture system from

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