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AB1248

Sigma-Aldrich

Anti-Cytochrome P450 Enzyme CYP1A2 Antibody

serum, Chemicon®

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eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_000761.3

UniProt accession no.

P05177

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... CYP1A2(1544)

Specificity

Reacts with human cytochrome P450 enzyme CYP1A2 in hepatic microsomal fraction. No cross-reactivity with other cytochrome P450 enzymes. By Western blot the antibody recognizes a protein with a molecular weight of approximately 54 kDa.

Immunogen

Synthetic peptide

Application

Anti-Cytochrome P450 Enzyme CYP1A2 Antibody is an antibody against Cytochrome P450 Enzyme CYP1A2 for use in IH & WB.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry
Western blot: 1:1,000-1:4,000

Immunohistochemistry on frozen and formaldehyde treated sections.

Optimal working dilutions must be determined by end user.

Linkage

Replaces: MAB3526

Physical form

Rabbit antiserum. Liquid. No preservatives

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Patricia Prieto et al.
Frontiers in physiology, 7, 548-548 (2016-12-03)
Stem cell therapy has emerged as a promising new area in regenerative medicine allowing the recovery of viable tissues. Among the many sources of adult stem cells, bone marrow-derived are easy to expand in culture via plastic adherence and their
Ting Xu et al.
Medical science monitor : international medical journal of experimental and clinical research, 26, e922149-e922149 (2020-04-15)
BACKGROUND Leonurine is an active component of the traditional Chinese medicine Leonurus japonicus. This study aimed to investigate the effects of overexpressed CYP450s on the metabolic activity of leonurine. MATERIAL AND METHODS BEAS-2B cells stably expressing CYP1A1, 1A2, 2A13, 2B6
M M Neis et al.
Skin pharmacology and physiology, 23(1), 29-39 (2010-01-22)
Organotypic skin models are frequently used for a wide range of applications and latterly also for dermatotoxicological studies. To evaluate their practicability for the investigation of xenobiotic metabolism in human skin we compared three types of organotypic skin models, acquired

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