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AB15452

Sigma-Aldrich

Anti-MAP2 Antibody

Chemicon®, from chicken

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Synonym(s):
Microtubule associated protein 2
eCl@ss:
32160702
NACRES:
NA.41

biological source

chicken

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

NCBI accession no.

NM_001039538.1
NM_002374.3
NM_031845.2
NM_031847.2

UniProt accession no.

P11137

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Map2(17756)

Specificity

MAP2 [Microtubule associated protein 2]
Other species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.

Immunogen

Synthetic peptides corresponding to different regions of the human/mouse MAP2 protein.

Application

Anti-MAP2 Antibody detects level of MAP2 & has been published & validated for use in IC, IH.
Immunohistochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed tissue.

Immunocytochemistry: 1:1000-1:2,000 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurofilament & Neuron Metabolism

Physical form

Affinity purified chicken immunoglobulin. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
ImmunoAffinity Purified

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

recommended

Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Hae-Jin Kweon et al.
Cell reports, 32(6), 108025-108025 (2020-08-14)
The α7 nicotinic acetylcholine receptor participates in diverse aspects of brain physiology and disease. Neurons tightly control α7 assembly, which relies upon NACHO, an endoplasmic reticulum (ER)-localized integral membrane protein. By constructing α7 chimeras and mutants, we find that NACHO
Yun Yang et al.
Nature communications, 13(1), 159-159 (2022-01-12)
Abnormalities in brain glucose metabolism and accumulation of abnormal protein deposits called plaques and tangles are neuropathological hallmarks of Alzheimer's disease (AD), but their relationship to disease pathogenesis and to each other remains unclear. Here we show that succinylation, a
J R Perez-Polo et al.
Journal of neuroscience research, 94(1), 27-38 (2015-07-15)
In rodent models of traumatic brain injury (TBI), both Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNFα) levels increase early after injury to return later to basal levels. We have developed and characterized a rat mild fluid percussion model of TBI
Andrew R Snavely et al.
Disease models & mechanisms, 15(12) (2022-11-19)
The proteosome inhibitor bortezomib has revolutionized the treatment of multiple hematologic malignancies, but in many cases, its efficacy is limited by a dose-dependent peripheral neuropathy. We show that human induced pluripotent stem cell (hiPSC)-derived motor neurons and sensory neurons provide
Madhurima Dhara et al.
Nature communications, 11(1), 2799-2799 (2020-06-05)
Small molecule polyamines are abundant in all life forms and participate in diverse aspects of cell growth and differentiation. Spermidine/spermine acetyltransferase (SAT1) is the rate-limiting enzyme in polyamine catabolism and a primary genetic risk factor for suicidality. Here, using genome-wide
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