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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC
Citations:
33
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
monkey, feline, rat, human, mouse, rabbit
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
suitability
not suitable for Western blot
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SLC6A1(6529)
Immunogen
Epitope: C-terminus (a.a. 588-599)
Rat GAT-1, C-terminus (aa 588-599)
Application
Anti-GABA Transporter-1 Antibody, C-terminus (a.a. 588-599) is an antibody against GABA Transporter-1 for use in IH.
Immunohistochemistry: 1:500-1:750 on 4% paraformaldehyde fixed or 4% paraformaldehyde and 0.2% glutaraldehyde fixed tissue. It is recommended that the antibody be diluted in PBS containing 10% normal goat serum and 0.5% Triton X-100. AB1570 has been used for both light and electron microscopic studies of rat retina, cortex and hippocampus.
Note: AB1570 is not recommended for Western blot use. See AB1570W.
Optimal working dilutions must be determined by the end user.
Note: AB1570 is not recommended for Western blot use. See AB1570W.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
GABA Transporter-1 (GAT-1), C-terminus. No cross-reactivity to the C-termini of other transmitter transporters detected.
Physical form
Affinity purified antibody. Lyophilized from in 0.1 M PBS with 1% BSA and 0.1% sodium azide. Reconstitute with 100 μL of sterile distilled water.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
Storage Class
11 - Combustible Solids
wgk
WGK 3
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
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The Journal of comparative neurology, 506(2), 240-262 (2007-11-21)
The acquisition of the dynamic balance between excitation and inhibition in developing Purkinje cells, necessary for their proper function, is analyzed. Newborn (P0) mouse cerebellum contains glutamatergic (VGLUT2-IR) and gamma-aminobutyric acid (GABA)-ergic (VIAAT-IR) axons. The former prevail and belong to
Elena E Bagley et al.
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Adaptations in neurons of the midbrain periaqueductal gray (PAG) induced by chronic morphine treatment mediate expression of many signs of opioid withdrawal. The abnormally elevated action potential rate of opioid-sensitive PAG neurons is a likely cellular mechanism for withdrawal expression.
Xinjun Wang et al.
The Journal of physiology, 592(19), 4257-4276 (2014-08-03)
GABAergic terminals of chandelier cells exclusively innervate the axon initial segment (AIS) of excitatory neurons. Although the anatomy of these synapses has been well-studied in several brain areas, relatively little is known about their physiological properties. Using vesicular γ-aminobutyric acid
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB1570 | 04053252334696 |
