AB5087
Anti-Melanocyte Stimulating Hormone α Antibody
serum, Chemicon®
Synonym(s):
alpha-MSH, POMC, Pro-opiomelanocortin, Corticotropin-lipotropin precursor
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, RIA
Technique(s):
immunohistochemistry: suitable, radioimmunoassay: suitable
Citations:
66
Uniprot accession no.:
biological source
sheep
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity (predicted by homology)
mammals
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, radioimmunoassay: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... POMC(5443)
Physical form
Sheep Serum. Liquid. Contains no preservative.
Unpurified
Analysis Note
Control
Hypothalamus
Hypothalamus
Application
Anti-Melanocyte Stimulating Hormone Antibody, α detects level of Melanocyte Stimulating Hormone & has been published & validated for use in IH, RIA.
Immunohistochemistry: 1:10,000-1:50,000 on 4% paraformaldehyde fixed tissue.
RIA: 1:250,000-1:300,000.
Optimal working dilutions must be determined by the end user.
RIA: 1:250,000-1:300,000.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
CNS Control of Metabolism
Hormones & Receptors
CNS Control of Metabolism
Hormones & Receptors
Biochem/physiol Actions
Specific for alpha-melanocyte stimulating hormone (aMSH), C-terminal.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
MSH conjugated with bovine thyroglobulin.
Preparation Note
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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B E Grayson et al.
Endocrinology, 151(4), 1622-1632 (2010-02-24)
The hypothalamic melanocortin system, which controls appetite and energy expenditure, develops during the third trimester in primates. Thus, maternal nutrition and health may have a profound influence on the development of this system. To study the effects of chronic maternal
Maja Cigrovski Berkovic et al.
Neuroendocrinology, 99(2), 75-84 (2014-04-02)
Although previously considered rare, recent epidemiological studies have revealed that the incidence (3.6/100,000) and prevalence (35/100,000) of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the past few decades. Despite the progress in the understanding of GEP-NET molecular biology, there is
Fumihiko Maekawa et al.
Frontiers in synaptic neuroscience, 5, 7-7 (2013-10-10)
We previously reported that the type 2 diabetic Goto-Kakizaki (GK) rats at young adult ages (6-12 weeks) exhibited increased visceral fat mass and hyperleptinemia, due to hyperphagia caused primarily by neuropeptide Y (NPY) overexpression in the hypothalamic arcuate nucleus. Later
Gavin A Bewick et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(12), 1680-1682 (2005-08-16)
Agouti-related protein (AgRP) and neuropeptide Y (NPY) are colocalized in arcuate nucleus (arcuate) neurons implicated in the regulation of energy balance. Both AgRP and NPY stimulate food intake when administered into the third ventricle and are up-regulated in states of
Angela M Ramos-Lobo et al.
eLife, 8 (2019-01-30)
Leptin regulates energy balance and also exhibits neurotrophic effects during critical developmental periods. However, the actual role of leptin during development is not yet fully understood. To uncover the importance of leptin in early life, the present study restored leptin
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