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AB5370

Sigma-Aldrich

Anti-Capsaicin Receptor Antibody, CT

serum, Chemicon®

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Synonym(s):
Vanilloid Receptor 1, VR1
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TRPV1(7442)

Specificity

Capsaicin Receptor (Vanilloid Receptor 1, VR1).

Immunogen

A 21 amino acid peptide corresponding to the C-terminus of the rat Capsaicin Receptor protein.
Epitope: C-terminus

Application

Detect Capsaicin Receptor using this Anti-Capsaicin Receptor Antibody, C-terminus validated for use in IH.
Immunohistochemistry: 1:2,000. The antibody reacts well with tissue from the rat dorsal root ganglia.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuroinflammation & Pain

Neurotransmitters & Receptors

Physical form

Serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.

Storage and Stability

Maintain lyophilized material at -20°C to -70°C for up to 6 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Otilia Obreja et al.
European journal of pain (London, England), 12(6), 775-789 (2008-01-26)
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels contribute to stabilizing resting membrane potential, thus controlling neuron excitability. Subclasses of nociceptive neurons differ in their excitability, therefore, these channels could be a distinguishing marker. We investigated isolated dorsal root ganglion neurons from a
Emily M Besecker et al.
Experimental neurology, 323, 113092-113092 (2019-11-08)
Dramatic impairment of gastrointestinal (GI) function accompanies high-thoracic spinal cord injury (T3-SCI). The vagus nerve contains mechano- and chemosensory fibers as well as the motor fibers necessary for the central nervous system (CNS) control of GI reflexes. Cell bodies for
Inge Brouns et al.
American journal of respiratory cell and molecular biology, 28(3), 275-285 (2003-02-21)
The characteristics of the different populations of sensory nerve terminals that selectively contact pulmonary neuroepithelial bodies (NEBs) in rat lungs were investigated after chemical denervation with capsaicin and compared with control lungs. Vagal calbindin D28k and P2X(3) purinoceptor immunoreactive (IR)
Jianzhong Lu et al.
PloS one, 16(1), e0243903-e0243903 (2021-01-08)
Tinnitus, the phantom perception of sound, often occurs as a clinical sequela of auditory traumas. In an effort to develop an objective test and therapeutic approach for tinnitus, the present study was performed in blast-exposed rats and focused on measurements

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