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Merck
CN

AB5663P

Anti-Histamine Receptor 4 Antibody, CT

Chemicon®, from rabbit

Synonym(s):

H4R

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-Histamine Receptor 4 Antibody, CT, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NM_021624.2

UniProt accession no.

Q9H3N8

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... HRH4(59340)

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

Anti-Histamine Receptor 4 Antibody, C-terminus detects level of Histamine Receptor 4 & has been published & validated for use in ELISA & WB.
Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
Western blot: 1-10 μg/mL using ECL.

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well (Catalog number AG217).

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Recognizes human Histamine Receptor 4 (HR4). The immunogen shows no significant sequence homology with other histamine receptors.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

A 17 amino acid peptide sequence within the cytoplasmic, C-terminus of human HR4 (Oda et al. 2000; Nakamura et al. 2000).
Epitope: C-terminus

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Denisha R Spires et al.
American journal of physiology. Renal physiology, 325(1), F105-F120 (2023-05-25)
Histamine is involved in the regulation of immune response, vasodilation, neurotransmission, and gastric acid secretion. Although elevated histamine levels and increased expression of histamine metabolizing enzymes have been reported in renal disease, there is a gap in knowledge regarding the
Functional role of histamine receptors in the renal cortical collecting duct cells.
Sudarikova, et al.
American Journal of Physiology. Cell Physiology, 322, C775-C786 (2023)

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