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AB9450

Sigma-Aldrich

Anti-Metabotropic Glutamate Receptor 6 Antibody

Chemicon®, from rabbit

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eCl@ss:
32160702

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)

NCBI accession no.

NM_000843.3

UniProt accession no.

O15303

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GRM6(2916)

Specificity

Recognizes Metabotropic Glutamate Receptor 6 [mGluR6].

Immunogen

Synthetic peptide from the N-terminal extracellular domain of human Metabotropic Glutamate Receptor 6.

Application

Immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections.

Western Blot

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-Metabotropic Glutamate Receptor 6 Antibody is validated for use in IH(P) for the detection of Metabotropic Glutamate Receptor 6.

Linkage

Replaces: AB5826

Physical form

Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with less than 0.1% sodium azide.

Storage and Stability

Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Dale D Hunter et al.
The Journal of comparative neurology, 527(1), 67-86 (2017-10-13)
The retina expresses several laminins in the outer plexiform layer (OPL), where they may provide an extracellular scaffold for synapse stabilization. Mice with a targeted deletion of the laminin β2 gene (Lamb2) exhibit retinal disruptions: photoreceptor synapses in the OPL

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