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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
conjugate
unconjugated
Quality Level
antibody form
affinity purified immunoglobulin
clone
polyclonal
species reactivity
rabbit, human
concentration
(Please refer to the Certificate of Analysis for the lot-specific concentration.)
technique(s)
immunohistochemistry: suitable
UniProt accession no.
target post-translational modification
unmodified
General description
FUNCTION: SwissProt: P32238 # Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
SIZE: 428 amino acids; 47841 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P32238 ## Belongs to the G-protein coupled receptor 1 family.
SIZE: 428 amino acids; 47841 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P32238 ## Belongs to the G-protein coupled receptor 1 family.
Synthetic peptide from the N-terminal extracellular domain of human Cholecystokinin A Receptor.
Application
Immunohistochemistry on paraffin embedded tissue sections.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes Cholecystokinin A Receptor.
Physical form
Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
Preparation Note
Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
10 - Combustible liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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