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ABC348

Anti-Bmf Antibody

Name: Anti-Bmf Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

Bcl-2-modifying factor, Bmf

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable, western blot: suitable

UniProt accession no.

Q96LC9

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... BMF(90427)

Description

General description

Bcl-2-modifying factor (Bmf) is a member of the Bcl-2 family containing one BCL2 homology domain 3. Members of this family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell′s actin cytoskeleton. Bmf is constitutively expressed in many tissues. There are 3 isoforms of Bmf. Isoform 1 is mainly expressed in B-lymphoid cells while isoform 2 and 3 are mainly expressed in B-CLL and normal B-cells.

~25 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to the N-terminus of human Bmf.

Application

Detect Bcl-2-modifying factor using this rabbit polyclonal antibody, Anti-Bmf Antibody validated for use in western blotting & IHC.

Immunocytochemistry Analysis: 10 µg/mL from a representative lot detected Bmf in HeLa cells.

Biochem/physiol Actions

This antibody recognizes the N-terminus of Bmf.

Analysis Note

Control
HepG2 and HEK293 cell lysates

Evaluated by Western Blotting in HepG2 and HEK293 cell lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected Bmf in 15 µg of HepG2 and HEK293 cell lysates.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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wgk

WGK 2

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Not applicable

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