Anti-Cathepsin Z Antibody

Cathepsin Z, also known as Cathepsin P, Cathepsin X, and encoded by the gene name CTSZ, is a member of the the peptidase C1 family. Cathepsin Z is a lysosomal cysteine proteinase that exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. Cathepsin Z is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. At least two transcript variants of this gene have been found, but the full-length nature of only one of them has been determined.

~33 kDa observed. (Pungecar, J., et al. (2000). PMID: 10653163)

Epitope: Near C-terminus

KLH-conjugated linear peptide corresponding to human Cathepsin Z near the C-terminus.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-Cathepsin Z antibody is validated for use in Western Blotting for the detection of Cathepsin Z.

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Cathepsin Z in 10 µg of human liver tissue lysate.

Concentration: Please refer to lot specific datasheet.

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