ABC841
Anti-Caspase-14 Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Caspase-14, CASP-14
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
-
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
immunohistochemistry: suitable, western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CASP14(23581)
General description
Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Caspase-14 exists as 2 subunits (p19 and p10) and is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
~28 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Immunogen
KLH-conjugated linear peptide corresponding to 16 amino acids near the C-terminus of human Caspase-14.
Application
Anti-Caspase-14 Antibody is a highly specific rabbit polyclonal antibody, that targets Caspase 14 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: 2.5 μg/mL from a representative lot detected Caspase-14 in human liver tissue.
Biochem/physiol Actions
This antibody detects the pro-form of Caspase-14 as well as the large subunit cleaved form.
Analysis Note
Evaluated by Western Blotting in Jurkat cell lysate with and without blocking peptide.
Western Blotting Analysis: 1 μg/mL of this antibody detected Caspase-14 in Jurkat cell lysate with and without blocking peptide.
Western Blotting Analysis: 1 μg/mL of this antibody detected Caspase-14 in Jurkat cell lysate with and without blocking peptide.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| ABC841 | 04053252940651 |