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Merck
CN

ABE1066

Sigma-Aldrich

Anti-phospho Exo1 (Ser746)

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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conjugate

unconjugated

antibody form

purified antibody

clone

polyclonal

purified by

affinity chromatography

species reactivity

rabbit, human

concentration

(Please refer to lot specific datasheet.)

technique(s)

dot blot: suitable
western blot: suitable

isotype

IgG

UniProt accession no.

target post-translational modification

phosphorylation (pSer746)

General description

KLH-conjugated linear peptide corresponding to 10 amino acids surrounding phosphoserine 746 from the C-terminal region of human Exonuclease 1.
~110 kDa observed; 94.10 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Application

Epitope: C-terminus

Biochem/physiol Actions

This rabbit polyclonal antibody detects Exonuclease 1 phosphorylated on Serine 746. It targets an epitope within 10 amino acids surrounding the phosphoserine 746 residue from the C-terminal region.

Physical form

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Analysis Note

Evaluated by Dot Blot with peptide phosphorylated on serine 746.

Dot Blot Analysis: 2.5 to 20 ng of this antibody detected phospho Exo1 (Ser746) in a peptide containing phosphoserine 746.

Other Notes

Human. Predicted to react with Monkey based on 100% sequence homology.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Regulatory Information

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