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Merck
CN

ABE211

Anti-CFP1 Antibody

serum, from rabbit

Synonym(s):

CXXC finger 1 (PHD domain), PHD finger and CXXC domain-containing protein 1, CXXC-type zinc finger protein 1, cpG-binding protein, CpG binding protein, zinc finger, CpG binding-type containing 1, DNA-binding protein with PHD finger and CXXC domain

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
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biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CXXC1(30827)

General description

CXXC finger protein 1 (CFP1) is part of the Setd1A and Setd1B methyltransferase compounds. Research shows that CFP1 also interacts with the cytosine methylation mechanism. CFP1 is necessary for development of mammals and is a key regulator of chromatin structure. Embryonic stem cells that are missing CFP1 are more susceptible to DNA-damaging agents and tend to build up more DNA damage. CFP1 has been shown to also be a regulator of DNA repair.
~78 kDa observed. A cross-reacting band observed at ~110 kDa

Immunogen

GST-tagged recombinant protein corresponding to human CFP1.

Application

Use Anti-CFP1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect CFP1 also known as CXXC finger 1 (PHD domain), cpG-binding protein.

Analysis Note

Evaluated by Western Blot in HeLa nuclear extract.

Western Blot Analysis: 1:1,000 dilution of this antibody detected CFP1 on 10 µg of HeLa nuclear extract.


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Storage Class

10 - Combustible liquids

wgk

WGK 1



Certificates of Analysis (COA)

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