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ABE604

Anti-Bonzo Antibody

Name: Anti-Bonzo Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

C-X-C chemokine receptor type 6, CXC-R6, CXCR-6, CDw186, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, CD186, BONZO, STRL33, TYMSTR

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable, western blot: suitable

UniProt accession no.

O00574

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CXCR6(10663)

Description

General description

G-protein coupled receptor bonzo (BONZO), also known as C-X-C chemokine receptor type 6 (CXCR6,CXC-R6,CXCR-6), CDw186 (CD186), G-protein coupled receptor STRL33 (STRL33), and TYMSTR, is a receptor for the C-X-C chemokine CXCL16 and is shown to be used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. Certain G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b have been identified as HIV coreceptors. BONZO is expressed in lymphoid tissues and activated T cells.

~45 kDa observed. Uncharacterized bands may appear in some lysate(s).

Immunogen

KLH-conjugated linear peptide corresponding to the N-terminus of human Bonzo.

Application

Detect CXCR6 using this rabbit polyclonal antibody, Anti-Bonzo Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 20 µg/mL from a representative lot detected Bonzo in human spleen tissue.

Biochem/physiol Actions

This antibody recognizes the N-terminus of Bonzo.

Analysis Note

Evaluated by Western Blotting/Peptide Inhibition Assay in human spleen tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected Bonzo in 15 µg of human spleen tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c