ABN466
Anti-NANOS2 Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Nanos homolog 2, NOS-2, NANOS2
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC, WB
Citations:
-
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, human
technique(s)
immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... NANOS2(339345)
General description
Nanos homolog 2 (NANOS2) is a zinc-finger containing, RNA-binding protein belonging to the nanos family. NANOS2 plays an important role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. It has been implicated in germ cell development in both invertebrates and vertebrates. Unlike NANOS1, whose expression in mice is dispensable, the NANOS2 and NANOS3 proteins are required for germ cell development. NANOS2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while NANOS3-null PGCs are lost during the migration stage regardless of sex.
~15 kDa observed
Immunogen
KLH-conjugated linear peptide corresponding to the N-terminus of human NANOS2.
Application
Detect Nanos homolog 2 using this rabbit polyclonal antibody, Anti-NANOS2 Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected NANOS2 in human brain tissue.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected NANOS2 in human testis cells.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected NANOS2 in human testis cells.
Biochem/physiol Actions
This antibody recognizes the N-terminus of NANOS2.
Analysis Note
Evaluated by Western Blotting in rat brain tissue.
Western Blotting Analysis: 2 µg/mL of this antibody detected NANOS2 in 15 µg of rat brain tissue.
Western Blotting Analysis: 2 µg/mL of this antibody detected NANOS2 in 15 µg of rat brain tissue.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Global Trade Item Number
| SKU | GTIN |
|---|---|
| ABN466 | 04053252870484 |