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COA/COQ

ABN58

Anti-phospho MAP1B (Thr1265) Antibody

Name: Anti-phospho MAP1B (Thr1265) Antibody
Brand: MM

from rabbit, purified by affinity chromatography

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Synonym(s):

Microtubule-associated protein 1B, MAP-1B, MAP1(X), MAP1.2, MAP1 light chain LC1

eCl@ss:

32160702

NACRES:

NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

species reactivity (predicted by homology)

mouse (immunogen homology)

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

P14873

shipped in

wet ice

target post-translational modification

phosphorylation (pThr1265)

Gene Information

mouse ... Map1B(17755)
rat ... Map1B(29456)

General description

Microtubule-associated protein 1B (MAP1B) is neuron-specific and is thought to play a part in controlling the neuronal cytoskeleton. MAP1B is made up of heavy and light chains and is involved in the microtubule and actin filament association. MAP1B may have an important role in axon formation by supporting microtubule dynamics and controlling cytoskeletal arrangement. MAP1B has also been associated with Netrin 1 signaling.

Specificity

Other homologies: Human (91% sequence homology).

This antibody recognizes MAP1B phosphorylated at Thr1265.

Immunogen

Epitope: Phosphorylated Thr1265

KLH-conjugated linear peptide corresponding to mouse MAP1B phosphorylated at Thr1265.

Application

Anti-phospho MAP1B (Thr1265) Antibody is an antibody against phospho MAP1B (Thr1265) for use in WB, IH & IC.

Immunohistochemistry Analysis: 1:600 dilution from a representative lot detected MAP1B in embryonic (E12) rat spinal cord tissue. (Image courtesy of Dr. Phillip R. Gordon-Weeks, King′s College London.)

Immunofluorescence Analysis: A representative lot was used by an independent laboratory in IF. (Trivedi, N., et al. (2005). Journal of Cell Science. 118:993-1005.)

Quality

Evaluated by Western Blot in S1 rat brain tissue lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected MAP1B on 10 µg of S1 rat brain tissue lysate.

Target description

~300 kDa observed

Analysis Note

Control
S1 rat brain tissue lysate

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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