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About This Item
UNSPSC Code:
12352202
NACRES:
NA.47
eCl@ss:
32160405
conjugate
unconjugated
concentration
1 mg/mL
technique(s)
inhibition assay: suitable
UniProt accession no.
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... UCP1(24860)
Application
Antibody blocking (AB3038)
Optimal working concentration must be determined by the end user.
Optimal working concentration must be determined by the end user.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
FUNCTION: SwissProt: P25874 # UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
SIZE: 307 amino acids; 33005 Da
SUBUNIT: Acts as a dimer forming a proton channel.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Brown adipose tissue.
SIMILARITY: SwissProt: P25874 ## Belongs to the mitochondrial carrier family. & Contains 3 Solcar repeats.
SIZE: 307 amino acids; 33005 Da
SUBUNIT: Acts as a dimer forming a proton channel.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Brown adipose tissue.
SIMILARITY: SwissProt: P25874 ## Belongs to the mitochondrial carrier family. & Contains 3 Solcar repeats.
Physical form
Liquid in PBS, pH 7.5 without a preservative
Preparation Note
Store at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Regulatory Information
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Certificates of Analysis (COA)
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