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Merck
CN

AQ503

Goat Anti-Human IgM+IgG+IgA Antibody, F(ab′)2

0.5 mg/mL, Chemicon®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
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Product Name

Goat Anti-Human IgM+IgG+IgA Antibody, F(ab′)2, 0.5 mg/mL, Chemicon®

biological source

goat

conjugate

unconjugated

antibody form

purified antibody

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

concentration

0.5 mg/mL

technique(s)

ELISA: suitable

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Related Categories

Application

Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
This Goat anti-Human IgM+IgG+IgA Antibody, F(ab′)2 is validated for use in ELISA for the detection of Human IgM+IgG+IgA.

Biochem/physiol Actions

Reacts with the heavy and light chains of human IgM, IgG and IgA, and with the light chains of human IgD.
The antibody reacts with the heavy and light chains of human IgM, IgG and IgA, and with the light chains of human IgD as demonstrated by ELISA and flow cytometry.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

IgG is the most abundant immunoglobulin comprising two heavy chains and two light chains. Each molecule has two antigen binding sites. IgG has 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). IgM constitutes about 10% of serum immunoglobulins. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces.

Immunogen

Epitope: Human IgM, IgG, IgA
Prepared from pepsin digest of human Ig.

Physical form

Gel filtration chromatography
Purified by gel filtration chromatography of pepsin digested antibody. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.

Preparation Note

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Hannah F Bradford et al.
Nature immunology, 25(5), 873-885 (2024-03-30)
Metabolic programming is important for B cell fate, but the bioenergetic requirement for regulatory B (Breg) cell differentiation and function is unknown. Here we show that Breg cell differentiation, unlike non-Breg cells, relies on mitochondrial electron transport and homeostatic levels

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