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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
20
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, rat, human
manufacturer/tradename
Chemicon®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SLC2A1(6513)
General description
46 kDa
Immunogen
12 amino acid peptide of the C-terminus of hGLUT-1 {LFHPLGADSQV} conjugated to KLH
Epitope: C-terminus
Application
Anti-Glucose Transporter GLUT-1 Antibody, C-terminus detects level of Glucose Transporter GLUT-1 & has been published & validated for use in IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Insulin/Energy Signaling
Insulin/Energy Signaling
Western blot analysis of GLUT-1 activity in adipose and muscle tissue (5μg/ml)
Immunoprecipitation of GLUT-1 (5μg/ml)
Optimal working dilutions must be determined by the end user.
Immunoprecipitation of GLUT-1 (5μg/ml)
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Specific for human glucose transporter 1 from muscle and adipose tissue. Does not cross-react with GLUT-4. The molecular weight of the glucose transporter precipitated by the serum is approximately 46 kDa.
Physical form
ImmunoAffinity Purified
The polyclonal is presented in phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Preparation Note
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to one year.
Analysis Note
Control
Colorectal carcinoma
Colorectal carcinoma
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
12 - Non Combustible Liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Angeliki Maria Nikolakopoulou et al.
The Journal of experimental medicine, 218(4) (2021-02-04)
The low-density lipoprotein receptor-related protein 1 (LRP1) is an endocytic and cell signaling transmembrane protein. Endothelial LRP1 clears proteinaceous toxins at the blood-brain barrier (BBB), regulates angiogenesis, and is increasingly reduced in Alzheimer's disease associated with BBB breakdown and neurodegeneration.
Fei Liu et al.
The European journal of neuroscience, 37(10), 1714-1725 (2013-02-26)
Deposition of β -amyloid (Aβ) peptides, cleavage products of β-amyloid precursor protein (APP) by β-secretase-1 (BACE1) and γ-secretase, is a neuropathological hallmark of Alzheimer's disease (AD). γ-Secretase inhibition is a therapeutical anti-Aβ approach, although changes in the enzyme's activity in
Altered metabolic and transporter characteristics of vastus lateralis in chronic obstructive pulmonary disease.
Green, HJ; Burnett, ME; D'Arsigny, CL; O'Donnell, DE; Ouyang, J; Webb, KA
Journal of Applied Physiology (1985)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| CBL242 | 04053252368295 |