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Mouse Leptin ELISA

This Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.

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Synonym(s):
Leptin, Obesity factor
eCl@ss:
32161000
NACRES:
NA.32

Quality Level

species reactivity

mouse

assay range

accuracy: 87-100%
linearity: 100-111%
sensitivity: 0.05 ng/mL
standard curve range: 0.2-30 ng/mL

technique(s)

ELISA: suitable

UniProt accession no.

detection method

colorimetric
fluorometric

General description

Mouse Leptin ELISA is used to measure and quantify leptin levels in metabolism, endocrine, and neuroscience research. Leptin is a hormone or cytokine derived from adipocytes circulating in the blood. It acts as a regulator of food intake and energy expenditure via the hypothalamus. This hormone plays a role in angiogenesis, lipid and carbohydrate metabolism, and hematopoiesis. Leptin exerts its effects on the cardiovascular, reproductive, and immune systems. The deficiency of leptin in rodents is associated with obesity and insulin resistance.

Application

Mouse Leptin ELISA has been used to determine the levels of leptin in mice serum and plasma.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Pictograms

CorrosionExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Met. Corr. 1 - Skin Sens. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3


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Candela Caballero-Eraso et al.
The Journal of physiology, 597(1), 151-172 (2018-10-05)
Leptin is a potent respiratory stimulant. A long functional isoform of leptin receptor, LepRb , was detected in the carotid body (CB), a key peripheral hypoxia sensor. However, the effect of leptin on minute ventilation (VE ) and the hypoxic
Leptin signalling
Sweeney G
Cellular Signalling, 14(8), 655-663 (2002)
Effects of castration on insulin levels and glucose tolerance in the mouse differ from those in man.
Takamitsu Inoue,Mahvash Zakikhani,Stephanie David,Carolyn Algire,Marie-Jose Blouin,Michael Pollak
Prostate null
Exogenous insulin enhances humoural immune responses in short-day, but not long-day, Siberian hamsters (Phodopus sungorus).
Garcia NW, Greives TJ, Zysling DA, French SS, Chester EM, Demas GE
Proceedings. Biological Sciences / The Royal Society null
Effect of chronic and intermittent calorie restriction on serum adiponectin and leptin and mammary tumorigenesis.
Rogozina OP, Bonorden MJ, Seppanen CN, Grande JP, Cleary MP
Cancer Prevention Research (Philadelphia, Pa.) null

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