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FCMAB135F

Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10

clone 2A10, Milli-Mark®, from mouse

Synonym(s):

Bone morphogenetic protein-7, osteogenic protein-1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
FITC conjugate
Clone:
2A10, monoclonal
Application:
FACS
Citations:
1

Key Documents

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biological source

mouse

conjugate

FITC conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2A10, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgG1κ

NCBI accession no.

NP_001710.1

UniProt accession no.

P18075

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... BMP7(655)

Related Categories

General description

46kDa Observed
Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.

Immunogen

Epitope: Unknown
Recombinant full-length BMP-7 protein.

Application

Working Solution Cells / test Total Reaction Volume
5 μl 5 x 105 Cells / 95 μl PBS 100 μl
10 μl 1 x 106 Cells / 90 μl PBS 100 μl
Detect BMP-7 using this Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10 validated for use in FC.
Research Category
Stem Cell Research
Research Sub Category
Mesenchymal Stem Cells

Biochem/physiol Actions

This monoclonal antibody recognizes BMP-7.

Physical form

Protein G Purified
Purified mouse monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
HeLa cells.
Evaluated by flow cytometry using HeLa cells.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Unconjugated antibody (MAB4350) also reacts against Mouse.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Veronica Veschi et al.
Oncogene, 39(5), 987-1003 (2019-10-09)
Despite intense research and clinical efforts, patients affected by advanced colorectal cancer (CRC) have still a poor prognosis. The discovery of colorectal (CR) cancer stem cell (CSC) as the cell compartment responsible for tumor initiation and propagation may provide new

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