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HCCBP1MAG-58K

MILLIPLEX® Human Circulating Cancer Biomarker Panel

Configurable Human Circulating Cancer Biomarker 25-Plex Panel 1

Synonym(s):

human cancer biomarker immunoassay panel, luminex human circulating cancer biomarkers multiplex assay, millipore human circulating cancer biomarkers multiplex kit, Luminex human circulating cancer biomarkers multiplex assay, Millipore human circulating cancer biomarkers multiplex kit

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Key Documents

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Product Name

MILLIPLEX® Human Circulating Cancer Biomarker Panel,

species reactivity

human

Quality Level

200

description

Configurable Human Circulating Cancer Biomarker 25-Plex Panel 1

assay range

accuracy: 35-108%, standard curve range: 0.09-67 mU/mL
(β-HCG), standard curve range: 0.7-500 pg/mL
(IL-6), standard curve range: 1.3-1000 pg/mL
(IL-8, TNFα), standard curve range: 2.7-2000 pg/mL
(TRAIL, TGF-α), standard curve range: 6.9-5000 pg/mL
(SCF)

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

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General description

Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 25 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: α-Fetoprotein (AFP), CA125, CA15-3, CA19-9, CEA, CYFRA21-1, sFas (TNFRSF6), sFasL, FGF-2 (FGF-basic), β-HCG (HCGβ), HE4, HGF, IL-6, IL-8 (CXCL8), Leptin, MIF, Osteopontin (OPN), Prolactin, PSA (free)*, PSA (total)*, SCF, TGFα, TNFα, TRAIL (TNFSF10), VEGF

Note: Total PSA and Free PSA cannot be plexed together.Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Extensive 25-Plex Analyte Panel: This kit allows for the simultaneous quantification of 25 specific cancer biomarkers, including α-Fetoprotein (AFP), CA125, CA15-3, CA19-9, CEA, and many others, enabling comprehensive cancer analysis.
  • Flexible Sample Types: Suitable for human serum, plasma, and tissue/cell culture supernatants or lysates, making it versatile for various research applications.
  • Comprehensive Insights into Tumor Biology: By measuring multiple circulating cancer biomarkers simultaneously, researchers can gain deeper insights into tumor dynamics, host response, and the tumor microenvironment.
  • Reliable and Accurate Results: The inclusion of internal quality controls and lyophilized standards ensures that assay performance is consistent, leading to trustworthy results.
  • User-Friendly Setup: The comprehensive kit contains everything needed for the assay, simplifying the setup process and reducing the likelihood of errors during preparation.
  • Enhanced Research Efficiency: The ability to perform multiplex analysis allows for increased throughput, enabling researchers to analyze more samples in less time, which is critical in high-volume research settings.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Information

新产品
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Sandra Tuyaerts et al.
Frontiers in nutrition, 5, 138-138 (2019-01-29)
Curcumin is a botanical with anti-tumor and immunomodulatory properties. We hypothesized that curcumin supplementation might influence inflammatory biomarker levels in endometrial carcinoma (EC). In this open-label, non-randomized phase 2 study (NCT02017353), seven EC patients consumed 2 g/day Curcumin Phytosome (CP)
Angela L Jefferson et al.
Journal of Alzheimer's disease : JAD, 52(2), 539-559 (2016-03-12)
Vascular health factors frequently co-occur with Alzheimer's disease (AD). A better understanding of how systemic vascular and cerebrovascular health intersects with clinical and pathological AD may inform prevention and treatment opportunities. To establish the Vanderbilt Memory & Aging Project, a
Daniel Ajona et al.
Translational research : the journal of laboratory and clinical medicine, 233, 77-91 (2021-02-23)
Lung cancer screening detects early-stage cancers, but also a large number of benign nodules. Molecular markers can help in the lung cancer screening process by refining inclusion criteria or guiding the management of indeterminate pulmonary nodules. In this study, we
Jonathan A Kluge et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(21), 5892-5897 (2016-05-11)
Advanced personalized medical diagnostics depend on the availability of high-quality biological samples. These are typically biofluids, such as blood, saliva, or urine; and their collection and storage is critical to obtain reliable results. Without proper temperature regulation, protein biomarkers in
A J Prati et al.
Journal of dental research, 92(12 Suppl), 161S-167S (2013-10-26)
The aim of this study was to compare the release of bone markers during osseointegration of immediately loaded and nonloaded implants. Forty patients who were indicated for rehabilitation with dental implants randomly received either implant and prosthesis placement within 72
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Quality Control Range Sheet- HCCA-115R and HCCA-215R
Quality Control Range Sheet- HCCA-115 and HCCA-215
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