Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Application
Simultaneously analyze 48 analytes in human cell culture supernatants.Analytes included: sCD40L, EGF, Eotaxin/CCL11, FGF-2/FGF-basic, FLT-3L, Fractalkine/CX3CL1, G-CSF, GM-CSF, GROα, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p40), IL-12(p70), IL-13, IL-15, IL-17A/CTLA8, IL-17E/IL-25, IL-17F, IL-18, IL-22, IL-27, IP-10/CXCL10, MCP-1/CCL2, MCP-3/CCL7, M-CSF, MDC, MIG/CXCL9, MIP-1α/CCL3, MIP-1β/CCL4, PDGF-AA, PDGF-AB/BB, RANTES/CCL5, TGFα, TNFα, TNFβ/LTA, VEGF-A
Disclaimer
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Features and Benefits
Lead the Field with 48-Plex Precision: The ability to profile 48 analytes simultaneously means researchers can uncover intricate cytokine interactions and pathways that are essential for understanding complex diseases.Designed for Human Cell Culture Supernatants: Optimized for analyzing cytokines, chemokines, and growth factors in cell culture supernatants.Disease Profiling Power: Proven utility in profiling immune responses in cancer, sepsis, IBD, and autoimmune diseases. Detects subtle changes in cytokine levels across disease states.High Biological Relevance: Analytes selected for their roles in inflammation, immune regulation, angiogenesis, and cell signaling, including key biomarkers like IL-6, TNFα, IL-10, VEGF-A, and PDGF-BB.Peer-Reviewed Validation: Extensively cited in immunology and disease research publications. Trusted by academic and clinical researchers worldwide.
General description
Cytokines, chemokines, and growth factors are key mediatorsof immune system functions capable of signaling through autocrine, paracrine,and endocrine mechanisms. Their pleiotropic immunomodulatory propertiesallow these biomolecules to react to diverse stimuli and regulate the immuneresponse, either promoting or inhibiting inflammation.
