MILLIPLEX^® Human Kidney Injury Panel

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in human urine samples.Analytes included: α-1-Microglobulin, Albumin, Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, Osteopontin (OPN)Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features:• 7-plex multiplexing allows simultaneous quantification of seven kidney injury biomarkers in human urine samples• Includes α-1-Microglobulin, Albumin, Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, and Osteopontin (OPN)• Magnetic bead-based format improves assay precision and simplifies washing steps• Utilizes Luminex^® xMAP^® technology for high-throughput analysis with minimal sample volume• Validated for use with human urine samples• Compatible with both manual and automated workflows Benefits:• Enables early detection of renal injury before traditional markers show abnormalities• Provides comprehensive coverage of biomarkers involved in nephrotoxicity and renal dysfunction• Conserves valuable samples by measuring multiple analytes in a single assay• Accelerates research in drug development, toxicology, and translational studies• Delivers high sensitivity and specificity with minimal cross-reactivity

Clusterin, Cystatin C, Lipocalin-2/NGAL, Osteopontin, and Uromodulin are key biomarkers associated with kidney injury, inflammation, and tubular function. These analytes provide insights into early renal damage, immune response, and epithelial integrity, making them valuable for studying acute kidney injury, chronic kidney disease, and nephrotoxicity. Their combined measurement supports comprehensive assessment of renal health and disease progression.